Electrophilic sulfhydration of 8-nitro-cGMP involves sulfane sulfur.

نویسندگان

  • V Terzić
  • D Padovani
  • V Balland
  • I Artaud
  • E Galardon
چکیده

The formation of 8-SH-cGMP from the reaction between hydrogen sulfide and 8-nitro-guanosine-3',5'-cyclic monophosphate in the presence of thiols does not take place by nucleophilic attack of the hydrosulfide anion, as previously proposed, but first involves the formation of reactive species containing sulfane sulfur, like persulfides.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 12 29  شماره 

صفحات  -

تاریخ انتشار 2014